Over the last few decades, there had been increasing interest in both microfluidics and wearables, especially for remote, continuous monitoring and management of health and fitness. The rapid emergence of the wearables market has been influenced by big tech companies producing the likes of the Apple Watch, Fitbit and other wearable devices. The integration of microfluidic technology with multiplex capabilities into wearable devices is one of the most highly anticipated next-generation technologies. It has particular relevance in the fields of healthcare diagnostics, point-of-care (POC) testing and fitness monitoring with great potential to be applied to many more applications and market opportunities including the military.